Why Does Massage Therapy Work?

My current goal is to promote the value of massage therapy by synthesizing and simplifying noteworthy finds and best available supporting evidence applicable to massage therapy.

Here I have put together a post defining massage therapy as well as an overview outlining potential responses to massage therapy

Massage Therapy: The Biopsychosocial Framework

A biopsychosocial framework helps put into context the interconnected and multidirectional interaction between: physiology, thoughts, emotions, behaviors, culture, and beliefs. In terms of clinical responses to massage therapy there are a couple of proposed mechanisms of action, including but not limited to:

• Neurodynamics - “A clinical concept that uses movement (1) to assess increased mechanosensitivity of the nervous system; and (2) to restore the altered homeostasis in and around the nervous system.” (Grieve's Modern Musculoskeletal Physiotherapy).

• Neuroplasticity - Touch can help sharpen the image of the self in our body maps.

• Contextually Aided Responses- The way we present ourselves and present our techniques is tied to clinical outcomes, the magnitude of a response may be influenced by mood, expectation, and conditioning.

• Neuromodulation - Massage has an affect on peripheral and central processes - input from large sensory neurons may prevent the spinal cord from amplifying nociceptive signaling.

• Social Grooming - Nervous system regulated by touch (social grooming) helps modulate the activity of neural circuits important for maintaining resting state. This reduced physiological and behavioural reactivity to stressors results in improved mood/affect.

• Mechanotherapy - "Any intervention that introduces mechanical forces with the goal of altering molecular pathways and inducing a cellular response that enhances tissue growth, modeling, remodeling, or repair.” (Thompson et al. 2016).


More to Explore

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https://www.ncbi.nlm.nih.gov/pubmed/27797730

Best, T.M., Gharaibeh, B., Huard, J. (2013). Stem cells, angiogenesis and muscle healing: a potential role in massage therapies? Br J Sports Med.
https://www.ncbi.nlm.nih.gov/pubmed/23197410

Bialosky, J.E., Beneciuk, J.M., Bishop, M.D., ... George, S.Z. (2017). Unraveling the Mechanisms of Manual Therapy: Modeling an Approach. J Orthop Sports Phys Ther.
https://www.ncbi.nlm.nih.gov/pubmed/29034802

Bialosky, J.E., Bishop, M.D., Penza, C.W. (2017). Placebo Mechanisms of Manual Therapy: A Sheep in Wolf's Clothing? J Orthop Sports Phys Ther.
https://www.ncbi.nlm.nih.gov/pubmed/28459190

Bishop, M. D., Torres-Cueco, R., Gay, C. ... Bialosky, J. E. (2015). What effect can manual therapy have on a patient's pain experience? Pain Management. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26401979 

Bove, G.M., Chapelle, S.L., Hanlon, K.E., Diamond, M.P., Mokler, D.J. (2017). Attenuation of postoperative adhesions using a modeled manual therapy. PLoS One. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28574997/ 

Bove, G.M., Harris, M.Y., Zhao, H., Barbe, M.F. (2016). Manual therapy as an effective treatment for fibrosis in a rat model of upper extremity overuse injury. J Neurol Sci. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26810536

Boudier-Revéret, M., Gilbert, K.K., Sobczak, S. (2017). Effect of neurodynamic mobilization on fluid dispersion in median nerve at the level of the carpal tunnel: A cadaveric study. Musculoskelet Sci Pract.
https://www.ncbi.nlm.nih.gov/pubmed/28734168

Chen, L., Michalsen, A. (2017). Management of chronic pain using complementary and integrative medicine. BMJ.
https://www.ncbi.nlm.nih.gov/pubmed/28438745

Courtney, C.A., Fernández-de-Las-Peñas, C., Bond, S. (2017). Mechanisms of chronic pain - key considerations for appropriate physical therapy management. J Man Manip Ther.
https://www.ncbi.nlm.nih.gov/pubmed/28694674

Ellingsen, D., Leknes, S., Løseth, G., Wessberg, J., & Olausson, H. (2016). The Neurobiology Shaping Affective Touch: Expectation, Motivation, and Meaning in the Multisensory Context. Frontiers in Psychology. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26779092

Fryer, G. (2017). Integrating osteopathic approaches based on biopsychosocial therapeutic mechanisms. Part 1: The mechanisms. International Journal of Osteopathic Medicine.
http://www.sciencedirect.com/science/article/pii/S1746068917300317

Fryer, G. (2017). Integrating osteopathic approaches based on biopsychosocial therapeutic mechanisms. Part 2: Clinical approach. International Journal of Osteopathic Medicine.
http://www.sciencedirect.com/science/article/pii/S1746068917300536

Habig, K., Schänzer, A., Schirner, W., ... Krämer, H.H. (2017). Low threshold unmyelinated mechanoafferents can modulate pain. BMC Neurol. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28915853

Louw, A., Nijs, J., Puentedura, E. (2017). A clinical perspective on a pain neuroscience education approach to manual therapy. Journal of Manual & Manipulative Therapy.
https://www.ncbi.nlm.nih.gov/pubmed/28694679

Mancini, F., Nash, T., Iannetti, G.D., Haggard, P. (2014). Pain relief by touch: a quantitative approach. Pain. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/24361816

Mancini, F., Beaumont, A., Hu, L., Haggard, P., & Iannetti, G. D. (2015). Touch inhibits subcortical and cortical nociceptive responses. Pain. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26058037

Melzack, R. & Wall, P.D. (1965). Pain mechanisms: a new theory. Science.
http://www.ncbi.nlm.nih.gov/pubmed/5320816

Miller, B.F., Hamilton, K.L., ... Butterfield, T.A., Dupont-Versteegden, E.E. (2017). Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non-massaged hind limb. J Physiol.
https://www.ncbi.nlm.nih.gov/pubmed/29090454

Morikawa, Y., Takamoto, K., Nishimaru, H., ... Nishijo, H. (2017). Compression at Myofascial Trigger Point on Chronic Neck Pain Provides  Pain Relief through the Prefrontal Cortex and Autonomic Nervous System: A Pilot Study. Front Neurosci. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28442987 

Newell, D., Lothe, L.R., Raven, T.J. (2017). Contextually Aided Recovery (CARe): a scientific theory for innate healing. Chiropr Man Therap. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28289539

Nummenmaa, L., Tuominen, L., Dunbar, R., ... Sams, M. (2016). Social touch modulates endogenous μ-opioid system activity in humans. Neuroimage.
https://www.ncbi.nlm.nih.gov/pubmed/27238727

Pelletier, R., Bourbonnais, D., Higgins, J. (2017). Nociception, pain, neuroplasticity and the practice of Osteopathic Manipulative Medicine. Journal of Manual & Manipulative Therapy.
http://www.sciencedirect.com/science/article/pii/S1746068917300111

Rabey, M., Hall, T., Hebron, C., Palsson, T.S., Christensen, S.W., Moloney, N. (2017). Reconceptualising manual therapy skills in contemporary practice. Musculoskeletal Science and Practice.
https://www.ncbi.nlm.nih.gov/pubmed/28286240

Thompson, W. R., Scott, A., Loghmani, M. T., Ward, S. R., & Warden, S. J. (2016). Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation. Physical Therapy. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26637643 

Vigotsky, A. D., & Bruhns, R. P. (2015). The Role of Descending Modulation in Manual Therapy and Its Analgesic Implications. Pain Research and Treatment. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26788367 

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https://www.ncbi.nlm.nih.gov/pubmed/28162847