Four Science Backed Ways Massage Makes You Feel Better

My current goal is to promote the value of massage therapy by synthesizing and simplifying noteworthy finds and best available supporting evidence applicable to massage therapy.

My current goal is to promote the value of massage therapy by synthesizing and simplifying noteworthy finds and best available supporting evidence applicable to massage therapy.

Four Science Backed Ways Massage Makes You Feel Better

The responses to massage therapy are multifactorial - physiological and psychological factors interplay in a complex manner. The biopsychosocial model provides a practical framework for investigating the complex interplay between massage therapy and clinical outcomes.

Based off the biopsychosocial model, investigation into mechanisms of action should extend beyond local tissue changes and include peripheral and central endogenous pain modulation. An observed favorable outcome may be explained by a number of overlapping mechanism in the periphery, spinal cord, and brain represented in the image below.

Proposed Therapeutic Mechanisms of Massage


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Best, T. M., & Crawford, S. K. (2017). Massage and postexercise recovery: The science is emerging. British Journal of Sports Medicine.
https://www.ncbi.nlm.nih.gov/pubmed/27797730

Best, T.M., Gharaibeh, B., Huard, J. (2013). Stem cells, angiogenesis and muscle healing: a potential role in massage therapies? Br J Sports Med.
https://www.ncbi.nlm.nih.gov/pubmed/23197410

Bialosky, J.E., Beneciuk, J.M., Bishop, M.D., ... George, S.Z. (2018). Unraveling the Mechanisms of Manual Therapy: Modeling an Approach. J Orthop Sports Phys Ther.
https://www.ncbi.nlm.nih.gov/pubmed/29034802

Bove, G.M., Chapelle, S.L., Hanlon, K.E., Diamond, M.P., Mokler, D.J. (2017). Attenuation of postoperative adhesions using a modeled manual therapy. PLoS One. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28574997/ 

Bove, G.M., Harris, M.Y., Zhao, H., Barbe, M.F. (2016). Manual therapy as an effective treatment for fibrosis in a rat model of upper extremity overuse injury. J Neurol Sci. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26810536

Boudier-Revéret, M., Gilbert, K.K., Sobczak, S. (2017). Effect of neurodynamic mobilization on fluid dispersion in median nerve at the level of the carpal tunnel: A cadaveric study. Musculoskelet Sci Pract.
https://www.ncbi.nlm.nih.gov/pubmed/28734168

Chen, L., Michalsen, A. (2017). Management of chronic pain using complementary and integrative medicine. BMJ.
https://www.ncbi.nlm.nih.gov/pubmed/28438745

Chimenti, R.L., Frey-Law, L.A., Sluka, K.A. (2018). A Mechanism-Based Approach to Physical Therapist Management of Pain. Phys Ther.
https://www.ncbi.nlm.nih.gov/pubmed/29669091/

Courtney, C.A., Fernández-de-Las-Peñas, C., Bond, S. (2017). Mechanisms of chronic pain - key considerations for appropriate physical therapy management. J Man Manip Ther.
https://www.ncbi.nlm.nih.gov/pubmed/28694674

Crane, J.D., Ogborn, D.I., ... Tarnopolsky, M.A. (2012). Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage. Sci Transl Med. https://www.ncbi.nlm.nih.gov/pubmed/22301554

Ellingsen, D., Leknes, S., Løseth, G., Wessberg, J., & Olausson, H. (2016). The Neurobiology Shaping Affective Touch: Expectation, Motivation, and Meaning in the Multisensory Context. Frontiers in Psychology. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26779092

Habig, K., Schänzer, A., Schirner, W., ... Krämer, H.H. (2017). Low threshold unmyelinated mechanoafferents can modulate pain. BMC Neurol. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28915853

Lloyd, D.M., McGlone, F.P., Yosipovitch, G. (2015). Somatosensory pleasure circuit: from skin to brain and back. Exp Dermatol.
https://www.ncbi.nlm.nih.gov/pubmed/25607755

Louw, A., Nijs, J., Puentedura, E. (2017). A clinical perspective on a pain neuroscience education approach to manual therapy. Journal of Manual & Manipulative Therapy.
https://www.ncbi.nlm.nih.gov/pubmed/28694679

Mancini, F., Beaumont, A., Hu, L., Haggard, P., & Iannetti, G. D. (2015). Touch inhibits subcortical and cortical nociceptive responses. Pain. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26058037

Melzack, R. & Wall, P.D. (1965). Pain mechanisms: a new theory. Science.
http://www.ncbi.nlm.nih.gov/pubmed/5320816

Miller, B.F., Hamilton, K.L., ... Butterfield, T.A., Dupont-Versteegden, E.E. (2018). Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non-massaged hind limb. J Physiol.
https://www.ncbi.nlm.nih.gov/pubmed/29090454

Morikawa, Y., Takamoto, K., Nishimaru, H., ... Nishijo, H. (2017). Compression at Myofascial Trigger Point on Chronic Neck Pain Provides Pain Relief through the Prefrontal Cortex and Autonomic Nervous System: A Pilot Study. Front Neurosci. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28442987 

Newell, D., Lothe, L.R., Raven, T.J. (2017). Contextually Aided Recovery (CARe): a scientific theory for innate healing. Chiropr Man Therap. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/28289539

Nummenmaa, L., Tuominen, L., Dunbar, R., ... Sams, M. (2016). Social touch modulates endogenous μ-opioid system activity in humans. Neuroimage.
https://www.ncbi.nlm.nih.gov/pubmed/27238727

Rabey, M., Hall, T., Hebron, C., Palsson, T.S., Christensen, S.W., Moloney, N. (2017). Reconceptualising manual therapy skills in contemporary practice. Musculoskeletal Science and Practice.
https://www.ncbi.nlm.nih.gov/pubmed/28286240

Rapaport, M.H., Schettler, P., Larson, E.R., ... Kinkead, B. (2016). Acute Swedish Massage Monotherapy Successfully Remediates Symptoms of Generalized Anxiety Disorder: A Proof-of-Concept, Randomized Controlled Study. J Clin Psychiatry.
https://www.ncbi.nlm.nih.gov/pubmed/27464321/

Rossettini, G., Carlino, E., Testa, M. (2018). Clinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeletal pain. BMC Musculoskelet Disord. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/29357856

Thompson, W. R., Scott, A., Loghmani, M. T., Ward, S. R., & Warden, S. J. (2016). Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation. Physical Therapy. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26637643 

Vigotsky, A. D., & Bruhns, R. P. (2015). The Role of Descending Modulation in Manual Therapy and Its Analgesic Implications. Pain Research and Treatment. (OPEN ACCESS)
https://www.ncbi.nlm.nih.gov/pubmed/26788367 

Walker, S.C., Trotter, P.D., Swaney, W.T., Marshall, A., Mcglone, F.P. (2017). C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides.
https://www.ncbi.nlm.nih.gov/pubmed/28162847 

Waters-Banker, C., Dupont-Versteegden, E. E., Kitzman, P. H., & Butterfield, T. A. (2014). Investigating the Mechanisms of Massage Efficacy: The Role of Mechanical Immunomodulation. Journal of Athletic Training. (Open Access)
https://www.ncbi.nlm.nih.gov/pubmed/24641083

Zhu, G.C., Tsai, K.L., Chen, Y.W., Hung, C.H. (2018). Neural Mobilization Attenuates Mechanical Allodynia and Decreases Proinflammatory Cytokine Concentrations in Rats With Painful Diabetic Neuropathy. Phys Ther. 
https://www.ncbi.nlm.nih.gov/pubmed/29309710